MRC1L1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, E |
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Primary Accession | P22897 |
Other Accession | Q5VSK2, NP_001009567.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 166012 Da |
Antigen Region | 359-388 aa |
Gene ID | 4360 |
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Other Names | Macrophage mannose receptor 1, MMR, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, Macrophage mannose receptor 1-like protein 1, CD206, MRC1, CLEC13D, CLEC13DL, MRC1L1 |
Target/Specificity | This MRC1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 359-388 amino acids from the N-terminal region of human MRC1L1. |
Dilution | WB~~1:2000 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MRC1L1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MRC1 |
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Synonyms | CLEC13D, CLEC13DL, MRC1L1 |
Function | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. |
Cellular Location | Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a type I membrane receptor protein highly related to the mannose receptor C type 1 protein (MRC1). The two genes are located near each other on chromosome 10 in a region thought to represent a segmental duplication.
REFERENCES
Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)

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