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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   TAS2R7 Antibody (C-term)   

TAS2R7 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - TAS2R7 Antibody (C-term) AP16822b
    TAS2R7 Antibody (C-term) (Cat. #AP16822b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TAS2R7 antibody detected the TAS2R7 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9NYW3
Other Accession NP_076408.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 36550 Da
Antigen Region 208-235 aa
Additional Information
Gene ID 50837
Other Names Taste receptor type 2 member 7, T2R7, Taste receptor family B member 4, TRB4, TAS2R7
Target/Specificity This TAS2R7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-235 amino acids from the C-terminal region of human TAS2R7.
Dilution WB~~1:1000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTAS2R7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TAS2R7
Function Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.

REFERENCES

Go, Y., et al. Genetics 170(1):313-326(2005)
Fischer, A., et al. Mol. Biol. Evol. 22(3):432-436(2005)
Zhang, Y., et al. Cell 112(3):293-301(2003)
Montmayeur, J.P., et al. Curr. Opin. Neurobiol. 12(4):366-371(2002)
Margolskee, R.F. J. Biol. Chem. 277(1):1-4(2002)

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