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>   首页   >   产品   >   一抗   >   代谢   >   GLUD2 Antibody (N-term)   

GLUD2 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - GLUD2 Antibody (N-term) AP20104a
    GLUD2 Antibody (N-term) (Cat. #AP20104a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GLUD2 antibody detected the GLUD2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P49448
Other Accession NP_036216.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 61434 Da
Antigen Region 75-103 aa
Additional Information
Gene ID 2747
Other Names Glutamate dehydrogenase 2, mitochondrial, GDH 2, GLUD2, GLUDP1
Target/Specificity This GLUD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human GLUD2.
Dilution WB~~1:1000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGLUD2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GLUD2
Synonyms GLUDP1
Function Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission.
Cellular Location Mitochondrion matrix
Tissue Location Expressed in retina, testis and, at a lower level, brain
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.

REFERENCES

Spanaki, C., et al. J. Biol. Chem. 285(22):16748-16756(2010)
Plaitakis, A., et al. Eur. J. Hum. Genet. 18(3):336-341(2010)
Zaganas, I., et al. Neurochem. Int. 55 (1-3), 52-63 (2009) :
Mastorodemos, V., et al. Biochem. Cell Biol. 87(3):505-516(2009)
Kanavouras, K., et al. J. Neurochem. 109 SUPPL 1, 167-173 (2009) :

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