癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TEX101 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BY14 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 26667 Da |
| Gene ID | 83639 |
|---|---|
| Other Names | Testis-expressed sequence 101 protein, Cell surface receptor NYD-SP8, Scleroderma-associated autoantigen, Spermatogenesis-related gene protein, TEX101, SGRG |
| Target/Specificity | This TEX101 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 214-246 amino acids from the C-terminal region of human TEX101. |
| Dilution | WB~~1:500-1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TEX101 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TEX101 (HGNC:30722) |
|---|---|
| Synonyms | SGRG |
| Function | Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q9JMI7}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9JMI7}. Membrane raft {ECO:0000250|UniProtKB:Q9JMI7}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9JMI7}. Secreted {ECO:0000250|UniProtKB:Q9JMI7}. Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q9JMI7}. Note=Located on plasma membrane of spermatocytes, round and elongated spermatids, and testicular spermatozoa. {ECO:0000250|UniProtKB:Q9JMI7} |
| Tissue Location | Detected in testis and spermatogonia. Not detected in spermatocytes. Detected in blood leukocytes |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity).
REFERENCES
Teng X.,et al.Biochem. Biophys. Res. Commun. 342:1223-1227(2006).
Li J.M.,et al.Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
Yang J.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
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Cat# AP20841c
