癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
(DANRE) dlc Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q9IAT6 |
| Reactivity | Zebrafish |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 72548 Da |
| Gene ID | 30120 |
|---|---|
| Other Names | Delta-like protein C, DeltaC, delC, dlc |
| Target/Specificity | This DANRE dlc antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 557-591 amino acids from DANRE dlc. |
| Dilution | WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | (DANRE) dlc Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | dlc |
|---|---|
| Function | Acts as a ligand for Notch receptors and is involved in somitogenesis. Can activate Notch receptors. Required in somite segmentation to keep the oscillations of neighboring presomitic mesoderm cells synchronized. |
| Cellular Location | Membrane; Single-pass type I membrane protein |
| Tissue Location | Strongly expressed in the early retina, where it precedes other delta proteins. Also expressed in cranial ganglia, in sensory epithelia including ear and lateral line and in scattered epidermal cells. In the mesoderm, expression is visible by 50% epiboly; it is expressed subsequently in the tail bud, in stripes in the presomitic mesoderm and in the posterior half of each somite. Also expressed in notochord, blood vessels and pronephros. In contrast to other delta proteins, it is not expressed in the majority of nascent primary neurons. In somites, it marks the posterior part of each formed somite, while deltaD (dld) marks the anterior part |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Acts as a ligand for Notch receptors and is involved in somitogenesis. Can activate Notch receptors. Required in somite segmentation to keep the oscillations of neighboring presomitic mesoderm cells synchronized.
REFERENCES
Smithers L.E.,et al.Mech. Dev. 90:119-123(2000).
Jiang Y.-J.,et al.Nature 408:475-479(2000).
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¥ 1,250.00
Cat# AP21638b
