癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
MTUS2 Antibody (C-Term) 精选
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, E |
|---|---|
| Primary Accession | Q5JR59 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 150195 Da |
| Gene ID | 23281 |
|---|---|
| Other Names | Microtubule-associated tumor suppressor candidate 2, Cardiac zipper protein, Microtubule plus-end tracking protein TIP150, Tracking protein of 150 kDa, MTUS2, CAZIP, KIAA0774, TIP150 |
| Target/Specificity | This MTUS2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 917-949 amino acids from human MTUS2. |
| Dilution | WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MTUS2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | MTUS2 |
|---|---|
| Synonyms | CAZIP, KIAA0774, TIP150 |
| Function | Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip. |
| Cellular Location | Cytoplasm, cytoskeleton. Note=Associated with the microtubule network at the growing distal tip (the plus-end) of microtubules |
| Tissue Location | Detected in embryonic stem cells differentiating to cardiomyocytes. |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip.
REFERENCES
Nagase T.,et al.DNA Res. 5:277-286(1998).
Ohara O.,et al.Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham A.,et al.Nature 428:522-528(2004).
Du Puy L.,et al.Dev. Dyn. 238:2903-2911(2009).
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