Phospho-JMJD1B(S291) Antibody
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
Application ![]()
| DB, E |
---|---|
Primary Accession | Q7LBC6 |
Other Accession | NP_057688.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 191581 Da |
Gene ID | 51780 |
---|---|
Other Names | Lysine-specific demethylase 3B, 11411-, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCA, KDM3B, C5orf7, JHDM2B, JMJD1B, KIAA1082 |
Target/Specificity | This JMJD1B Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S291 of human JMJD1B. |
Dilution | DB~~1:500 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Phospho-JMJD1B(S291) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KDM3B |
---|---|
Synonyms | C5orf7, JHDM2B, JMJD1B, KIAA1082 |
Function | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. |
Cellular Location | Nucleus. |
Tissue Location | Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
REFERENCES
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Yamane, K., et al. Cell 125(3):483-495(2006)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)

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