癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Phospho-PDHE1A(S232) Antibody
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 文献引用 : 2
- 实验流程
Application 
| DB, E |
|---|---|
| Primary Accession | P08559 |
| Other Accession | P26284, P29804, P35486, Q8HXW9, A7MB35, NP_000275.1 |
| Reactivity | Human |
| Predicted | Bovine, Monkey, Mouse, Pig, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Calculated MW | 43296 Da |
| Gene ID | 5160 |
|---|---|
| Other Names | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, PDHE1-A type I, PDHA1, PHE1A |
| Target/Specificity | This PDHE1A Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S232 of human PDHE1A. |
| Dilution | DB~~1:500 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Phospho-PDHE1A(S232) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PDHA1 |
|---|---|
| Synonyms | PHE1A |
| Function | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. |
| Cellular Location | Mitochondrion matrix. |
| Tissue Location | Ubiquitous. |
Research Areas
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Author : Agnihotri S1, Golbourn B2, Huang X3, Remke M2, Younger S4, Cairns RA5, Chalil A2, Smith CA2, Krumholtz SL2, Mackenzie D2, Rakopoulos P2
Cancer Res. 2016 Jun 20. [Epub ahead of print] |
27325644 |
|
Author : Sun W1,Xie Z1,Liu Y2,Zhao D3,Wu Z4,Zhang D1,Lv H1,Tang S1,Jin N1,Jiang H3,Tan M4,Ding J1,Luo C5,Li J6,Huang M7,Geng M7. Cancer Res. 2015 Nov 15;75(22):4923-36. doi: 10.1158/0008-5472.CAN-15-1023. Epub 2015 Oct 19. |
26483203 |
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,100.00
Cat# AP3758A
