RDH10 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application ![]()
| IHC-P, FC, WB, E |
---|---|
Primary Accession | Q8IZV5 |
Other Accession | Q80ZF7, Q8VCH7, Q8HZT6 |
Reactivity | Human, Rat, Mouse |
Predicted | Bovine, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 38087 Da |
Antigen Region | 106-135 aa |
Gene ID | 157506 |
---|---|
Other Names | Retinol dehydrogenase 10, RDH10 |
Target/Specificity | This RDH10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the Central region of human RDH10. |
Dilution | IHC-P~~1:100~500 FC~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | RDH10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RDH10 |
---|---|
Synonyms | SDR16C4 |
Function | Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol. |
Cellular Location | Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein |
Tissue Location | Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
RDH10 generates all-trans retinal from all-trans retinol and may plan an important role in the photic visual cycle. All-trans retinal is isomerized to 11-cis retinal by the retinal G protein-coupled receptor (RGR; MIM 600342) when the retinal pigment epithelium (RPE) is illuminated.
REFERENCES
Bankovic, J., et al. Lung Cancer 67(2):151-159(2010)
Takahashi, Y., et al. Biochem. J. 419(1):113-122(2009)
Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009)

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