FAST Kinase Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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Application ![]()
| WB, ICC |
---|---|
Primary Accession | Q14296 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 61104 Da |
Gene ID | 10922 |
---|---|
Other Names | Fas-activated serine/threonine kinase, FAST kinase, FASTK |
Dilution | WB~~1:1000 ICC~~N/A |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | FASTK |
---|---|
Function | Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro- apoptotic form of the receptor. |
Cellular Location | [Isoform 4]: Mitochondrion matrix. Note=Colocalizes with mitochondrial RNA granules. |
Tissue Location | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor.
REFERENCES
Tian Q.,et al.J. Exp. Med. 182:865-874(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 424:157-164(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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