|Reactivity||Human, Mouse, Rat|
|Calculated MW||37 KDa|
|Other Names||Poly(rC)-binding protein 1, Alpha-CP1, Heterogeneous nuclear ribonucleoprotein E1, hnRNP E1, Nucleic acid-binding protein SUB23, PCBP1|
|Target/Specificity||KLH conjugated synthetic peptide derived from human hnRNP E1|
|Format||0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. In case of infection by poliovirus, plays a role in initiation of viral RNA replication in concert with the viral protein 3CD (PubMed:12414943).|
|Cellular Location||Nucleus. Cytoplasm. Note=Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm|
|Tissue Location||Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands|
Provided below are standard protocols that you may find useful for product applications.
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC.
Leffers H.,et al.Eur. J. Biochem. 230:447-453(1995).
Kiledjian M.,et al.EMBO J. 14:4357-4364(1995).
Aasheim H.-C.,et al.Nucleic Acids Res. 22:959-964(1994).
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Olsen J.V.,et al.Cell 127:635-648(2006).