Anti-COVID-19 Envelope Protein Antibody
- 产品详情
- 实验流程
Application
| WB, E |
|---|---|
| Primary Accession | P0DTC4 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 8365 Da |
| Gene ID | 43740570 |
|---|---|
| Other Names | Envelope small membrane protein; E protein; sM protein |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of COVID-19 Envelope Protein. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/1000 - 1/3000) E~~N/A |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | E {ECO:0000255|HAMAP-Rule:MF_04204} |
|---|---|
| Function | Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis (By similarity). Regulates the localization of S protein at cis-Golgi, the place of virus budding (PubMed:33229438). May act by slowing down the cell secretory pathway (PubMed:33229438). May interfere with tight-junction stability by interacting with host MPP5. This would result in disruption of epithelial barriers, thereby amplifying inflammatory processes (PubMed:32891874). |
| Cellular Location | Host Golgi apparatus membrane {ECO:0000255|HAMAP- Rule:MF_04204}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_04204, ECO:0000269|PubMed:32898469, ECO:0000269|PubMed:33177698}. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal. {ECO:0000255|HAMAP-Rule:MF_04204} |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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