GHRH Rabbit pAb
GHRH Rabbit pAb
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Application 
  | IHC-P, IHC-F, IF | 
|---|---|
| Primary Accession | P01286 | 
| Reactivity | Pig, Mouse | 
| Host | Rabbit | 
| Clonality | Polyclonal | 
| Calculated MW | 12447 Da | 
| Physical State | Liquid | 
| Immunogen | KLH conjugated synthetic peptide derived from human GHRF | 
| Epitope Specificity | 32-59/103 | 
| Isotype | IgG | 
| Purity | affinity purified by Protein A | 
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. | 
| SUBCELLULAR LOCATION | Secreted. | 
| SIMILARITY | Belongs to the glucagon family. | 
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. | 
| Background Descriptions | GHRF encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. | 
| Gene ID | 2691 | 
|---|---|
| Other Names | Somatoliberin, Growth hormone-releasing factor, GRF, Growth hormone-releasing hormone, GHRH, Somatocrinin, Somatorelin, Sermorelin, GHRH, GHRF | 
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 | 
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. | 
| Name | GHRH | 
|---|---|
| Synonyms | GHRF | 
| Function | GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone. | 
| Cellular Location | Secreted. | 
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
GHRF encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.
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