癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
PTPLAD2 Rabbit pAb
PTPLAD2 Rabbit pAb
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q5VWC8 |
| Reactivity | Human |
| Predicted | Rat, Pig, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 27520 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human PTPLAD2 |
| Epitope Specificity | 1-100/232 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Membrane; Multi pass membrane protein |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | PTPLAD2 is a protein that belongs to the PTPLA family. The function of PTPLAD2 remains unknown. |
| Gene ID | 401494 |
|---|---|
| Other Names | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4, 4.2.1.134, 3-hydroxyacyl-CoA dehydratase 4, HACD4, Protein-tyrosine phosphatase-like A domain-containing protein 2 {ECO:0000312|HGNC:HGNC:20920}, HACD4 {ECO:0000303|PubMed:18554506, ECO:0000312|HGNC:HGNC:20920} |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | HACD4 {ECO:0000303|PubMed:18554506, ECO:0000312|HGNC:HGNC:20920} |
|---|---|
| Function | Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Tissue Location | Highly expressed in leukocytes, and low expression in heart, spleen, kidney, and placenta. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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