癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SDS/Serine dehydratase Rabbit pAb
SDS/Serine dehydratase Rabbit pAb
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Application 
| WB |
|---|---|
| Primary Accession | P20132 |
| Reactivity | Human |
| Predicted | Mouse, Rat, Rabbit, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 34625 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human SDS/Serine dehydratase |
| Epitope Specificity | 201-300/328 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the serine/threonine dehydratase family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008] |
| Gene ID | 10993 |
|---|---|
| Other Names | L-serine dehydratase/L-threonine deaminase, SDH, 4.3.1.17, Hepatic serine dehydratase, hSDH, L-serine deaminase, L-threonine dehydratase, TDH, 4.3.1.19, SDS, SDH |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | SDS |
|---|---|
| Synonyms | SDH |
| Function | Catalyzes the pyridoxal-phosphate-dependent dehydrative deamination of L-threonine and L-serine to ammonia and alpha- ketobutyrate and pyruvate, respectively. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P09367}. |
| Tissue Location | Predominantly expressed in the perivenous regions of the liver. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008]
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