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>   首页   >   产品   >   一抗   >   精选抗体   >   Anti-SHB (pY246) Antibody   

Anti-SHB (pY246) Antibody

Rabbit polyclonal antibody to SHB (pY246)

     
  • 1 - Anti-SHB (pY246) Antibody AP59699
    Western blot analysis of SHB (pY246) expression in Hela (A), A375 (B), rat kidney (C), rat spleen (D) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q15464
Other Accession Q6PD21
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 55042 Da
Additional Information
Gene ID 6461
Other Names SH2 domain-containing adapter protein B
Target/Specificity Recognizes endogenous levels of SHB (pY246) protein.
Dilution WB~~WB (1/500 - 1/1000)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name SHB
Function Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin- producing cells.
Cellular Location Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associates with membrane lipid rafts upon TCR stimulation
Tissue Location Widely expressed..
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SHB. The exact sequence is proprietary.

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