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Anti-EOMES Antibody

Rabbit polyclonal antibody to EOMES

     
  • 1 - Anti-EOMES Antibody AP59738
    Western blot analysis of EOMES expression in BV2 (A), C6 (B), A549 (C), Jurkat (D) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession O95936
Other Accession O54839
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 72732 Da
Additional Information
Gene ID 8320
Other Names TBR2; Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2
Target/Specificity Recognizes endogenous levels of EOMES protein.
Dilution WB~~WB (1/500 - 1/1000)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name EOMES
Synonyms TBR2
Function Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex (PubMed:17353897). Required for differentiation and migration of unipolar dendritic brush cells (PubMed:33488348). Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes (PubMed:17566017).
Cellular Location Nucleus.
Tissue Location Expressed in CD8+ T-cells.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human EOMES. The exact sequence is proprietary.

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