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Anti-FASTKD2 Antibody

Rabbit polyclonal antibody to FASTKD2

     
  • 1 - Anti-FASTKD2 Antibody AP59811
    Western blot analysis of FASTKD2 expression in H446 (A), A549 (B), mouse liver (C), mouse lung (D), rat liver (E), rat lung (F) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IP
Primary Accession Q9NYY8
Other Accession Q922E6
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 81463 Da
Additional Information
Gene ID 22868
Other Names KIAA0971; FAST kinase domain-containing protein 2
Target/Specificity Recognizes endogenous levels of FASTKD2 protein.
Dilution WB~~WB (1/500 - 1/1000), IP (1/10 - 1/100)
IP~~N/A
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name FASTKD2 {ECO:0000303|PubMed:27667664, ECO:0000312|HGNC:HGNC:29160}
Function Plays an important role in assembly of the mitochondrial large ribosomal subunit (PubMed:25683715). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt- rRNA), controls 16S mt-rRNA abundance and is required for intra- mitochondrial translation (PubMed:25683715, PubMed:26370583, PubMed:27667664). May play a role in mitochondrial apoptosis.
Cellular Location Mitochondrion matrix, mitochondrion nucleoid Mitochondrion matrix. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids.
Tissue Location Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle and thyroid.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FASTKD2. The exact sequence is proprietary.

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