Anti-Angiopoietin-2 Antibody
Rabbit polyclonal antibody to Angiopoietin-2
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, IHC |
---|---|
Primary Accession | O15123 |
Other Accession | O35608 |
Reactivity | Human, Mouse, Rat, Monkey, Pig, Drosophila |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 56919 Da |
Gene ID | 285 |
---|---|
Other Names | Angiopoietin-2; ANG-2 |
Target/Specificity | Recognizes endogenous levels of Angiopoietin-2 protein. |
Dilution | WB~~WB (1/500 - 1/1000), IHC (1/50 - 1/200) IHC~~WB (1/500 - 1/1000), IHC (1/50 - 1/200) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | ANGPT2 |
---|---|
Function | Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling (PubMed:15284220, PubMed:19116766, PubMed:19223473, PubMed:9204896). Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1 (PubMed:15284220, PubMed:19116766, PubMed:19223473, PubMed:9204896). In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (PubMed:15284220, PubMed:19116766, PubMed:19223473, PubMed:9204896). Involved in the regulation of lymphangiogenesis (PubMed:32908006). |
Cellular Location | Secreted. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Angiopoietin-2. The exact sequence is proprietary.

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