Anti-BMPR2 Antibody
Rabbit polyclonal antibody to BMPR2
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB |
---|---|
Primary Accession | Q13873 |
Other Accession | O35607 |
Reactivity | Human, Mouse, Rat, Pig |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 115201 Da |
Gene ID | 659 |
---|---|
Other Names | PPH1; Bone morphogenetic protein receptor type-2; BMP type-2 receptor; BMPR-2; Bone morphogenetic protein receptor type II; BMP type II receptor; BMPR-II |
Target/Specificity | Recognizes endogenous levels of BMPR2 protein. |
Dilution | WB~~WB (1/500 - 1/1000) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | BMPR2 |
---|---|
Synonyms | PPH1 |
Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Can also mediate signaling through the activation of the p38MAPK cascade (PubMed:12045205). Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. Promotes signaling also by binding to activin A/INHBA (PubMed:24018044). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Highly expressed in heart and liver. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human BMPR2. The exact sequence is proprietary.

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