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Anti-RGMB Antibody

Rabbit polyclonal antibody to RGMB

     
  • 1 - Anti-RGMB Antibody AP59957
    Western blot analysis of RGMB expression in mouse brain (A), rat brain (B), Hela (C), HCT116 (D), A2780 (E), PC3 (F), SGC7901 (G) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q6NW40
Other Accession Q7TQ33
Reactivity Human, Mouse, Rat, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 47547 Da
Additional Information
Gene ID 285704
Other Names RGM domain family member B; DRG11-responsive axonal guidance and outgrowth of neurite; DRAGON
Target/Specificity Recognizes endogenous levels of RGMB protein.
Dilution WB~~WB (1/500 - 1/1000)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name RGMB {ECO:0000303|PubMed:19324014, ECO:0000312|HGNC:HGNC:26896}
Function Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q7TQ33}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q7TQ33}. Membrane raft {ECO:0000250|UniProtKB:Q7TQ33}
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human RGMB. The exact sequence is proprietary.

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