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>   首页   >   产品   >   一抗   >   其他   >   Anti-Glutathione Peroxidase Antibody   

Anti-Glutathione Peroxidase Antibody

Rabbit polyclonal antibody to Glutathione Peroxidase

     
  • 1 - Anti-Glutathione Peroxidase Antibody AP60810
    Western blot analysis of Glutathione Peroxidase expression in mouse liver (A), rat liver (B) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P07203
Other Accession P11352
Reactivity Human, Mouse, Rat, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 22088 Da
Additional Information
Gene ID 2876
Other Names Glutathione peroxidase 1; GPx-1; GSHPx-1; Cellular glutathione peroxidase
Target/Specificity Recognizes endogenous levels of Glutathione Peroxidase protein.
Dilution WB~~WB (1/500 - 1/2000)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name GPX1 (HGNC:4553)
Function Catalyzes the reduction of hydroperoxides in a glutathione- dependent manner thus regulating cellular redox homeostasis (PubMed:11115402, PubMed:36608588). Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides (PubMed:11115402, PubMed:36608588). In platelets catalyzes the reduction of 12-hydroperoxyeicosatetraenoic acid, the primary product of the arachidonate 12-lipoxygenase pathway (PubMed:11115402).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:P11352}. Mitochondrion {ECO:0000250|UniProtKB:P11352}
Tissue Location Expressed in platelets (at protein level).
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Glutathione Peroxidase. The exact sequence is proprietary.

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