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Anti-Myeloperoxidase 89k Antibody

Rabbit polyclonal antibody to Myeloperoxidase 89k

     
  • 1 - Anti-Myeloperoxidase 89k Antibody AP61038
    Western blot analysis of Myeloperoxidase 89k expression in Jurkat (A), K562 (B), SP20 (C) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P05164
Other Accession P11247
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 83869 Da
Additional Information
Gene ID 4353
Other Names Myeloperoxidase; MPO
Target/Specificity Recognizes endogenous levels of Myeloperoxidase 89k protein.
Dilution WB~~WB (1/500 - 1/1000)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name MPO (HGNC:7218)
Function Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity (PubMed:9922160). Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage (PubMed:25698971).
Cellular Location Lysosome.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Myeloperoxidase 89k. The exact sequence is proprietary.

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