Anti-CBX6 Antibody
Rabbit polyclonal antibody to CBX6
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, IHC |
---|---|
Primary Accession | O95503 |
Other Accession | Q9DBY5 |
Reactivity | Human, Mouse, Rat, Bovine, Drosophila |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 43898 Da |
Gene ID | 23466 |
---|---|
Other Names | Chromobox protein homolog 6 |
Target/Specificity | Recognizes endogenous levels of CBX6 protein. |
Dilution | WB~~WB (1/500 - 1/1000), IHC (1/50 - 1/200) IHC~~WB (1/500 - 1/1000), IHC (1/50 - 1/200) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | CBX6 |
---|---|
Function | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235). Recruitment to chromatin might occur in an H3K27me3- independent fashion (By similarity). May have a PRC1-independent function in embryonic stem cells (By similarity). |
Cellular Location | Nucleus. Chromosome. Note=Uniformely distributed in the nucleoplasm (PubMed:18927235). Localizes to the inactivated X chromosome in females (By similarity). {ECO:0000250|UniProtKB:Q9DBY5, ECO:0000269|PubMed:18927235} |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CBX6. The exact sequence is proprietary.

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Cat# AP61301