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>   首页   >   产品   >   一抗   >   其他   >   Anti-Myeloperoxidase Antibody   

Anti-Myeloperoxidase Antibody

Mouse monoclonal antibody to Myeloperoxidase

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC
Primary Accession P05164
Reactivity Human
Host Mouse
Clonality Monoclonal
Calculated MW 83869 Da
Additional Information
Gene ID 4353
Other Names Myeloperoxidase; MPO
Target/Specificity Recognizes endogenous levels of Myeloperoxidase protein.
Dilution IHC~~1:100~500
Format Mouse IgG2b. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name MPO (HGNC:7218)
Function Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity (PubMed:9922160). Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage (PubMed:25698971).
Cellular Location Lysosome.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

KLH-conjugated synthetic peptide encompassing a sequence within human Myeloperoxidase. The exact sequence is proprietary.

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