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>   首页   >   产品   >   一抗   >   发育生物学   >   SOX30 Antibody (Center)   

SOX30 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - SOX30 Antibody (Center) AP6278c
    Western blot analysis of lysate from K562 cell line, using SOX30 Antibody (Center)(Cat. #AP6278c). AP6278c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
Western blot analysis of lysate from K562 cell line, using SOX30 Antibody (Center)(Cat. #AP6278c). AP6278c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession O94993
Other Accession Q8CGW4, Q8WNV5
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 81854 Da
Antigen Region 373-403 aa
Additional Information
Gene ID 11063
Other Names Transcription factor SOX-30, SOX30
Target/Specificity This SOX30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 373-403 amino acids from the Central region of human SOX30.
Dilution WB~~1:1000
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSOX30 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX30
Function Acts both as a transcriptional activator and a repressor (PubMed:10359848, PubMed:29739711). Binds to the DNA sequence 5'-ACAAT- 3' and shows a preference for guanine residues surrounding this core motif (PubMed:10359848). Binds to its own promoter and activates its own transcription (By similarity). Required to activate the expression of postmeiotic genes involved in spermiogenesis (By similarity). Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling (PubMed:29739711). Also inhibits Wnt signaling by binding to the CTNNB1 protein, preventing interaction of CTNNB1 with TCF7L2/TCF4 (PubMed:29739711).
Cellular Location Nucleus. Cytoplasm Note=Enriched at the chromocenter. {ECO:0000250|UniProtKB:Q8CGW4}
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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