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FH Polyclonal Antibody

     
  • 1 - FH Polyclonal Antibody AP63391
    Western blot analysis of 1) Hela, 2) Mouse Brain, 3) HepG2, diluted at 1:2000.. Secondary antibody was diluted at 1:20000
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P07954
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 54637 Da
Additional Information
Gene ID 2271
Other Names Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)
Dilution WB~~WB: 1:1000
Format PBS, pH 7.4, containing 0.09% (W/V) sodium azide as Preservative and 50% Glycerol.
Storage Conditions-20℃
Protein Information
Name FH {ECO:0000303|PubMed:27037871, ECO:0000312|HGNC:HGNC:3700}
Function Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (PubMed:30761759). Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable).
Cellular Location [Isoform Mitochondrial]: Mitochondrion
Tissue Location Expressed in red blood cells; underexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Also acts as a tumor suppressor.

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