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ECP Polyclonal Antibody

     
  • 1 - ECP Polyclonal Antibody AP69639
    Western Blot analysis of various cells using ECP Polyclonal Antibody
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P12724
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 18385 Da
Additional Information
Gene ID 6037
Other Names RNASE3; ECP; RNS3; Eosinophil cationic protein; ECP; Ribonuclease 3; RNase 3
Dilution WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name RNASE3
Synonyms ECP, RNS3
Function Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Cellular Location Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.

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