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>   首页   >   产品   >   一抗   >   心血管   >   SELL Antibody (C-term)   

SELL Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 1 - SELL Antibody (C-term) AP6990B
    Western blot analysis of SELL Antibody (C-term) (Cat. #AP6990b) in Jurkat cell line lysates (35ug/lane).SELL (arrow) was detected using the purified Pab.
  • 14 - SELL Antibody (C-term) AP6990B
    Formalin-fixed and paraffin-embedded human lymph tissue with SELL Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • 4 - SELL Antibody (C-term) AP6990B
    Flow cytometric analysis of jurkat cells using SELL Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P, WB, FC, E
Primary Accession P14151
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 42187 Da
Antigen Region 346-372 aa
Additional Information
Gene ID 6402
Other Names L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, LAM-1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor, TQ1, gp90-MEL, CD62L, SELL, LNHR, LYAM1
Target/Specificity This SELL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-372 amino acids from the C-terminal region of human SELL.
Dilution IHC-P~~1:100~500
WB~~1:1000
FC~~1:10~50
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSELL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SELL
Synonyms LNHR, LYAM1
Function Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28011641, PubMed:28489325). Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (PubMed:12403782, PubMed:28011641).
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed in B-cell lines and T-lymphocytes.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

SELL is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins.

REFERENCES

Zebrowska,A., et.al., Pol J Pathol 60 (1), 26-34 (2009)

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