IGSF4C Polyclonal Antibody
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Application
| WB, IHC-P, IF, ICC, E |
|---|---|
| Primary Accession | Q8NFZ8 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 42785 Da |
| Gene ID | 199731 |
|---|---|
| Other Names | CADM4; IGSF4C; NECL4; TSLL2; Cell adhesion molecule 4; Immunoglobulin superfamily member 4C; IgSF4C; Nectin-like protein 4; NECL-4; TSLC1-like protein 2 |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. IHC-P~~1:50~200 IF~~1:50~200 ICC~~N/A E~~N/A |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CADM4 |
|---|---|
| Synonyms | IGSF4C, NECL4, TSLL2 |
| Function | Cell adhesion molecule, exhibiting calcium- and magnesium- independent cell-cell adhesion activity (PubMed:16261159). In its palmitoylated form, is required for proper oligodendrocyte maturation and myelination in CNS via its association with other cell adhesion molecules such as CADM2/3 and MAG (By similarity). May have tumor- suppressor activity (PubMed:16261159). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q8R464}; Single-pass type I membrane protein. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q8R464}; Single-pass type I membrane protein |
| Tissue Location | Expressed in brain, prostate, brain, kidney and some other organs. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity.
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