LASS4 Polyclonal Antibody
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Application ![]()
| WB, IHC-P |
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Primary Accession | Q9HA82 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 46399 Da |
Gene ID | 79603 |
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Other Names | CERS4; LASS4; Ceramide synthase 4; CerS4; LAG1 longevity assurance homolog 4 |
Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. IHC-P~~N/A |
Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
Storage Conditions | -20℃ |
Name | CERS4 {ECO:0000303|PubMed:17977534, ECO:0000312|HGNC:HGNC:23747} |
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Function | Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor. |
Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9D6J1}; Multi-pass membrane protein |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner (By similarity).

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Cat# AP70719