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PSCA Polyclonal Antibody

     
  • 1 - PSCA Polyclonal Antibody AP72060
    Western Blot analysis of various cells using PSCA Polyclonal Antibody diluted at 1:1000
  • 1 - PSCA Polyclonal Antibody AP72060
    Western Blot analysis of HepG2 cells using PSCA Polyclonal Antibody diluted at 1:1000
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession O43653
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 11959 Da
Additional Information
Gene ID 8000
Other Names PSCA; Prostate stem cell antigen
Dilution WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name PSCA
Function May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor
Tissue Location Highly expressed in prostate (basal, secretory and neuroendocrine epithelium cells). Also found in bladder (transitional epithelium), placenta (trophoblasts), stomach (neuroendocrine cells), colon (neuroendocrine cells) and kidney (collecting ducts) Overexpressed in prostate cancers and expression is correlated with tumor stage, grade and androgen-independence. Highly expressed in prostate cancer bone metastases. Expressed in gastric epithelial cells, mainly in the isthmus (at protein level). Not detected in normal intestinal epithelium (at protein level). Expressed in brain cortex; expression is significantly increased in the front cortex of Alzheimer disease patients.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.

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