CA14 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application
| WB, FC, E |
|---|---|
| Primary Accession | Q9ULX7 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 37668 Da |
| Antigen Region | 51-80 aa |
| Gene ID | 23632 |
|---|---|
| Other Names | Carbonic anhydrase 14, Carbonate dehydratase XIV, Carbonic anhydrase XIV, CA-XIV, CA14 |
| Target/Specificity | This CA14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-80 amino acids from the N-terminal region of human CA14. |
| Dilution | WB~~1:1000 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CA14 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CA14 |
|---|---|
| Function | Reversible hydration of carbon dioxide. |
| Cellular Location | Membrane; Single-pass type I membrane protein |
| Tissue Location | High expression in all parts of the central nervous system and lower expression in adult liver, heart, small intestine, colon, kidney, urinary bladder and skeletal muscle |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
CA14 belongs a large family of zinc metalloenzymes that catalyze the versible hydration of carbon dioxide. The protein is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles.
REFERENCES
Parkkila,S. Natl. Acad. Sci. U.S.A. 98 (4), 1918-1923 (2001)
Fujikawa-Adachi,K., Nishimori,I. Genomics 61 (1), 74-81 (1999)
Tarun,A.S., Bryant,B. Chem. Senses 28 (7), 621-629 (2003)
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