注册 | 登录
点击这里给我发消息
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   其他   >   Pax-5 Polyclonal Antibody   

Pax-5 Polyclonal Antibody

     
  • 1 - Pax-5 Polyclonal Antibody AP73495
    Western Blot analysis of 293 cells using Pax-5 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
  • 14 - Pax-5 Polyclonal Antibody AP73495
    Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100
  • 14 - Pax-5 Polyclonal Antibody AP73495
    Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100
  • 14 - Pax-5 Polyclonal Antibody AP73495
    Immunohistochemical analysis of paraffin-embedded mouse-spleen, antibody was diluted at 1:100
  • 14 - Pax-5 Polyclonal Antibody AP73495
    Immunohistochemical analysis of paraffin-embedded mouse-spleen, antibody was diluted at 1:100
  • 产品详情
  • 实验流程
  • 背景知识
Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P
Primary Accession Q02548
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 42149 Da
Additional Information
Gene ID 5079
Other Names PAX5; Paired box protein Pax-5; B-cell-specific transcription factor; BSAP
Dilution WB~~Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
IHC-P~~Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name PAX5
Function Transcription factor that plays an essential role in commitment of lymphoid progenitors to the B-lymphocyte lineage (PubMed:10811620, PubMed:27181361). Fulfills a dual role by repressing B-lineage inappropriate genes and simultaneously activating B-lineage- specific genes (PubMed:10811620, PubMed:27181361). In turn, regulates cell adhesion and migration, induces V(H)-to-D(H)J(H) recombination, facilitates pre-B-cell receptor signaling and promotes development to the mature B-cell stage (PubMed:32612238). Repression of the cohesin- release factor WAPL causes global changes of the chromosomal architecture in pro-B cells to facilitate the generation of a diverse antibody repertoire (PubMed:32612238).
Cellular Location Nucleus.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.

FeedBack

终于等到您。ABCEPTA(百远生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-88856768 tech-china@abcepta.com.


我要评价