IL-19 Polyclonal Antibody

Western blot analysis of 293T Hela VEC KB mouse-kidney lysate, antibody was diluted at 500. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P
Primary Accession	Q9UHD0
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Calculated MW	20452 Da

Additional Information
Gene ID	29949
Other Names	Interleukin-19 (IL-19) (Melanoma differentiation-associated protein-like protein) (NG.1)
Dilution	WB~~WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000 IHC-P~~WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Format	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions	-20℃

Protein Information
Name	IL19
Synonyms	ZMDA1
Function	Cytokine that functions as an anti-inflammatory and proangiogenic factor (PubMed:34932373). Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL13 (PubMed:16365913). Produced by osteocytes, stimulates granulopoiesis and neutrophil formation (By similarity). Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB (PubMed:12351624). In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3 (PubMed:11564763).
Cellular Location	Secreted.