FDFT1 Rabbit mAb
- 产品详情
- 实验流程
Application ![]()
| WB, IP, ICC |
---|---|
Primary Accession | P37268 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 48115 Da |
Gene ID | 2222 |
---|---|
Other Names | FDFT1 |
Dilution | WB~~1/500-1/1000 IP~~N/A ICC~~N/A |
Format | Liquid |
Name | FDFT1 |
---|---|
Function | Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of inorganic diphosphate. In the second half-reaction, PSQPP undergoes heterolysis, isomerization, and reduction with NADPH or NADH to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. |
Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q02769}; Multi-pass membrane protein |
Tissue Location | Widely expressed.. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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