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>   首页   >   产品   >   一抗   >   其他   >   FDFT1 Rabbit mAb   

FDFT1 Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IP, ICC
Primary Accession P37268
Reactivity Human, Rat
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 48115 Da
Additional Information
Gene ID 2222
Other Names FDFT1
Dilution WB~~1/500-1/1000
IP~~N/A
ICC~~N/A
Format Liquid
Protein Information
Name FDFT1
Function Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of inorganic diphosphate. In the second half-reaction, PSQPP undergoes heterolysis, isomerization, and reduction with NADPH or NADH to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway.
Cellular Location Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q02769}; Multi-pass membrane protein
Tissue Location Widely expressed..
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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