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>   首页   >   产品   >   一抗   >   其他   >   AZI2 Rabbit mAb   

AZI2 Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9H6S1
Reactivity Human, Rat
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 44935 Da
Additional Information
Gene ID 64343
Other Names AZI2
Dilution WB~~1/500-1/1000
Format Liquid
Protein Information
Name AZI2
Synonyms NAP1 {ECO:0000303|PubMed:14560022}, TBKB
Function Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity (PubMed:14560022, PubMed:21931631). Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization (PubMed:14560022, PubMed:21931631). Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1 (PubMed:14560022, PubMed:21931631). Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B (PubMed:14560022, PubMed:21931631). Participates in IFNB promoter activation via TICAM1 (PubMed:15611223).
Cellular Location Cytoplasm.
Tissue Location Widely expressed (PubMed:14560022). Abundant expression seen in the pancreas and testis (PubMed:14560022)
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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