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>   首页   >   产品   >   一抗   >   其他   >   HBEGF Rabbit mAb   

HBEGF Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q99075
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 23067 Da
Additional Information
Gene ID 1839
Other Names HBEGF
Dilution WB~~1/500-1/1000
Format Liquid
Protein Information
Name HBEGF
Synonyms DTR, DTS, HEGFL
Function Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
Cellular Location [Heparin-binding EGF-like growth factor]: Secreted, extracellular space. Note=Mature HB-EGF is released into the extracellular space and probably binds to a receptor
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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