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>   首页   >   产品   >   一抗   >   其他   >   Myeloperoxidase Rabbit mAb   

Myeloperoxidase Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P
Primary Accession P05164
Reactivity Human, Mouse
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 83869 Da
Additional Information
Gene ID 4353
Other Names MPO
Dilution WB~~1/500-1/1000
IHC-P~~N/A
Format Liquid
Protein Information
Name MPO (HGNC:7218)
Function Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity (PubMed:9922160). Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage (PubMed:25698971).
Cellular Location Lysosome.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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