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>   首页   >   产品   >   一抗   >   其他   >   PCPTP1 Rabbit mAb   

PCPTP1 Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q15256
Reactivity Rat
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 73834 Da
Additional Information
Gene ID 5801
Other Names PTPRR
Dilution WB~~1/500-1/1000
Format Liquid
Protein Information
Name PTPRR
Synonyms ECPTP, PTPRQ
Function Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).
Cellular Location Secreted. [Isoform Delta]: Cytoplasm, perinuclear region. Note=Locates to the perinuclear areas within the cytoplasm
Tissue Location Detected in cerebrospinal fluid (at protein level) (PubMed:25326458). Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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