alpha 1-Antitrypsin Rabbit mAb
- 产品详情
- 实验流程
Application ![]()
| WB, IP |
---|---|
Primary Accession | P01009 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 46737 Da |
Gene ID | 5265 |
---|---|
Other Names | SERPINA1 |
Dilution | WB~~1/500-1/1000 IP~~N/A |
Format | Liquid |
Name | SERPINA1 (HGNC:8941) |
---|---|
Synonyms | AAT, PI |
Function | Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. |
Cellular Location | Secreted. Endoplasmic reticulum. Note=The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum |
Tissue Location | Ubiquitous. Expressed in leukocytes and plasma. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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