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>   首页   >   产品   >   一抗   >   其他   >   MYH9 Rabbit mAb   

MYH9 Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IP
Primary Accession P35579
Reactivity Human, Rat
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 226532 Da
Additional Information
Gene ID 4627
Other Names MYH9
Dilution WB~~1/500-1/1000
IHC-P~~N/A
IP~~N/A
Format Liquid
Protein Information
Name MYH9
Function Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Required for cortical actin clearance prior to oocyte exocytosis (By similarity). Promotes cell motility in conjunction with S100A4 (PubMed:16707441). During cell spreading, plays an important role in cytoskeleton reorganization, focal contact formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10 (PubMed:20052411).
Cellular Location Cytoplasm, cytoskeleton. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q8VDD5}. Cytoplasmic vesicle, secretory vesicle, Cortical granule {ECO:0000250|UniProtKB:Q8VDD5}. Cell membrane Note=Colocalizes with actin filaments at lamellipodia margins and at the leading edge of migrating cells (PubMed:20052411). In retinal pigment epithelial cells, predominantly localized to stress fiber-like structures with some localization to cytoplasmic puncta (PubMed:27331610).
Tissue Location In the kidney, expressed in the glomeruli. Also expressed in leukocytes.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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