MDH1 Rabbit mAb
- 产品详情
- 实验流程
Application ![]()
| WB, FC, IP, ICC |
---|---|
Primary Accession | P40925 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 36426 Da |
Gene ID | 4190 |
---|---|
Other Names | MDH1 |
Dilution | WB~~1/500-1/1000 FC~~1:10~50 IP~~N/A ICC~~N/A |
Format | Liquid |
Name | MDH1 {ECO:0000303|PubMed:34012073, ECO:0000312|HGNC:HGNC:6970} |
---|---|
Function | Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH (PubMed:2449162, PubMed:3052244). Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation (PubMed:31538237). Catalyzes the reduction of 2-oxoglutarate to 2- hydroxyglutarate, leading to elevated reactive oxygen species (ROS) (PubMed:34012073). |
Cellular Location | Cytoplasm, cytosol. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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