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>   首页   >   产品   >   一抗   >   其他   >   delta Opioid Receptor Rabbit mAb   

delta Opioid Receptor Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC
Primary Accession P41143
Reactivity Rat, Human, Mouse
Host Rabbit
Clonality Monoclonal Antibody
Isotype IgG
Conjugate Unconjugated
Immunogen A synthesized peptide derived from human OPRD1
Purification Affinity Chromatography
Calculated MW 40369 Da
Additional Information
Gene ID 4985
Other Names OPRD1
Dilution WB~~1/500-1/1000
FC~~1:10~50
Format Liquid in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Protein Information
Name OPRD1
Synonyms OPRD
Function G-protein coupled receptor that functions as a receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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