WAPL Rabbit mAb
- 产品详情
- 实验流程
Application ![]()
| WB, IF, ICC, IP |
---|---|
Primary Accession | Q7Z5K2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Isotype | IgG |
Conjugate | Unconjugated |
Immunogen | A synthesized peptide derived from human WAPL |
Purification | Affinity Purified |
Calculated MW | 132946 Da |
Gene ID | 23063 |
---|---|
Other Names | WAPL |
Dilution | WB~~1/500-1/1000 IF~~1:50~200 ICC~~N/A IP~~N/A |
Format | Liquid in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Name | WAPL (HGNC:23293) |
---|---|
Synonyms | FOE, KIAA0261, WAPAL |
Function | Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin (PubMed:26299517). Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. |
Cellular Location | [Isoform 2]: Nucleus. |
Tissue Location | Isoform 1 is highly expressed in uterine cervix tumor. Isoform 2 is widely expressed with a high level in skeletal muscle and heart. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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