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>   首页   >   产品   >   一抗   >   精选抗体   >   WAPL Rabbit mAb   

WAPL Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, ICC, IP
Primary Accession Q7Z5K2
Reactivity Human
Host Rabbit
Clonality Monoclonal Antibody
Isotype IgG
Conjugate Unconjugated
Immunogen A synthesized peptide derived from human WAPL
Purification Affinity Purified
Calculated MW 132946 Da
Additional Information
Gene ID 23063
Other Names WAPL
Dilution WB~~1/500-1/1000
IF~~1:50~200
ICC~~N/A
IP~~N/A
Format Liquid in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Protein Information
Name WAPL (HGNC:23293)
Synonyms FOE, KIAA0261, WAPAL
Function Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin (PubMed:26299517). Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
Cellular Location [Isoform 2]: Nucleus.
Tissue Location Isoform 1 is highly expressed in uterine cervix tumor. Isoform 2 is widely expressed with a high level in skeletal muscle and heart.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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