癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
CETP Antibody
Rabbit mAb
- 产品详情
- 实验流程
Application 
| WB, IP |
|---|---|
| Primary Accession | P11597 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Other Names | BPIFF; HDLCQ10;CETP; Lipid transfer protein I; Cholesteryl ester transfer protein; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 54756 Da |
| Dilution | WB 1:500~1:2000 IP 1:50 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human CETP |
| Description | Cholesteryl ester transfer protein (CETP) is a circulating metabolic enzyme that transports cholesterol from the arteries to the liver. CETP converts cholesteryl esters from antiatherogenic high density lipoproteins (HDLs) to proatherogenicapolipoprotein B (apoB)-containing lipoproteins, including very low-, intermediate-, and low-DLs. Efficient transfer and exchange of cholesteryl esters and triglycerides between the lipoprotein classes of human plasma is necessary to maintain healthy arteries. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CETP (HGNC:1869) |
|---|---|
| Function | Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL (PubMed:24293641, PubMed:3281933, PubMed:3600759). Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (PubMed:17237796). |
| Cellular Location | Secreted. Note=Secreted in plasma |
| Tissue Location | Expressed by the liver and secreted in plasma. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP90343
