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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   Cytokeratin 5 Antibody   

Cytokeratin 5 Antibody

Rabbit mAb

     
  • 0 - Cytokeratin 5 Antibody AP90655
    Western blot analysis of Cytokeratin 5 expression in A431 cell lysate.
  • 0 - Cytokeratin 5 Antibody AP90655
    Immunohistochemical analysis of paraffin-embedded human skin, using Cytokeratin 5 Antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC, IF, ICC, IHF
Primary Accession P13647
Reactivity Rat, Human, Mouse
Clonality Monoclonal
Other Names 58 kDa cytokeratin; CK-5; CK5; Cytokeratin-5; DDD1; EBS2; K2C5; K5; keratin 5; Krt5;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 62378 Da
Additional Information
Dilution WB 1:5000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human Cytokeratin 5
Description The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name KRT5
Function Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity).
Cellular Location Cytoplasm.
Tissue Location Expressed in corneal epithelium (at protein level) (PubMed:26758872). Expressed in keratinocytes (at protein level) (PubMed:20128788, PubMed:31302245).
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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