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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   JAG1 Antibody   

JAG1 Antibody

Rabbit mAb

     
  • 1 - JAG1 Antibody AP90729
    Western blot analysis of JAG1 expression in HepG2 cell lysate.
  • 2 - JAG1 Antibody AP90729
    Immunohistochemical analysis of paraffin-embedded human kidney, using JAG1 Antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC
Primary Accession P78504
Reactivity Human
Clonality Monoclonal
Other Names JAG1; AGS; AHD; Alagille syndrome; CD339 antigen; HJ1; Jagged1; JAGL1; Jagged; Jagged 1; Protein jagged-1; AWS; CD339; Soluble protein jagged;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 133799 Da
Additional Information
Dilution WB 1:500~1:2000 IHC 1:50~1:200
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human JAG1
Description Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name JAG1
Synonyms JAGL1
Function Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (PubMed:18660822, PubMed:20437614). May be involved in cell-fate decisions during hematopoiesis (PubMed:9462510). Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).
Cellular Location Membrane; Single-pass type I membrane protein. Cell membrane
Tissue Location Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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