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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   MUC16 Antibody   

MUC16 Antibody

Rabbit mAb

     
  • 0 - MUC16 Antibody AP90739
    Western blot analysis of MUC16 expression in Human ovary cancer lysate.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, FC, ICC
Primary Accession Q8WXI7
Reactivity Human
Clonality Monoclonal
Other Names Cancer antigen 125; CA125; CA125 ovarian cancer; MUC 16; Mucin16; Ovarian cancer related tumor marker CA125;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 1519175 Da
Additional Information
Dilution WB 1:5000~1:20000 ICC/IF 1:50~1:200 FC 1:100
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human MUC16
Description The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name MUC16 (HGNC:15582)
Function Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
Cellular Location Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space. Note=May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain
Tissue Location Expressed in corneal and conjunctival epithelia (at protein level). Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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