GLP2 Antibody
Rabbit mAb
- 产品详情
- 实验流程
Application
| WB |
|---|---|
| Primary Accession | P01275 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Other Names | GCG; GLP 2; GRPP; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 20909 Da |
| Dilution | WB 1:500~1:2000 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human GLP2 |
| Description | Human GLP2 (glucagon like peptide 2) is a peptide hormone of the glucagon family produced by the L cells of the intestial mucosa and originates from the same prohormone as glucagon. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GCG (HGNC:4191) |
|---|---|
| Function | [Glucagon]: Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. Binds to and activates the glucagon receptor GCGR, which couples to the G(s) G protein and elevates intracellular cAMP, triggering downstream metabolic responses (PubMed:32193322). |
| Cellular Location | Secreted. |
| Tissue Location | [Glucagon]: Secreted in the A cells of the islets of Langerhans. [Glucagon-like peptide 2]: Secreted from enteroendocrine cells throughout the gastrointestinal tract. Also secreted in selected neurons in the brain [Oxyntomodulin]: Secreted from enteroendocrine cells throughout the gastrointestinal tract |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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